ANTIUROLITHIATIC ACTIVITY OF ETHANOLIC EXTRACT OF EICHHORNIA CRASSIPES (MART.) SOLMS WHOLE PLANT ON ETHYLENE GLYCOL-INDUCED UROLITHIASIS IN WISTAR RATS

Objective: In India Indigenous system of medicine, the plant Eichhornia crassipes (Mart.) Solms is claimed to be useful for different ailments. The purpose this study investigate significant activity ethanolic extract E. whole in treatment renal stone by ethylene glycol (EG)-induced urolithiasis Wistar rats. Methods: rat will divided into four groups. All animals received EG 0.75%v/v orally 28 days. Group I was Groups II, III, and IV were cystone, (200 mg/kg, 400 mg/kg), respectively, administered from 15th 28th day curative regimen. Animals housed metabolic cages collect 24 h urine samples serum on 7th, 14th, 21th, experiments. Under microscopical observe crystals sample. biochemical parameters monitored present are calcium, oxalate, magnesium, phosphorus, urea, creatinine, uric acid, blood urea nitrogen (BUN), lactate dehydrogenase (LDH) samples. Results: feeding resulted elevated excretion phosphate, decreased magnesium as well-elevated BUN, LDH levels, pH volume. Treatment significantly reduced oxalate well level serum. It also restores normal promotes output. Conclusion: Ethanolic exhibited anti-urolithiatic evident levels levels.